Cancer continues to impact millions of lives every year. Out of over 200 identified types, just 13 of them account for more than 70% of new yearly cancer cases in the U.S. Understanding these common cancers—including how they form, symptoms, and survival outlook—can help with early detection, prevention, and better care decisions.
📋 List of the 13 Most Common Cancers (U.S.)
Here’s a breakdown of the most commonly diagnosed cancers in the United States, ranked by estimated new yearly cases:
1. Breast Cancer
The most frequently diagnosed cancer in American women. It may also occur in men, although rarely.
Estimated yearly new cases: ~270,000
5-year survival rate: ~90% (female)
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2. Lung Cancer (including bronchus)
The leading cause of cancer-related death. Often linked to smoking, but non-smokers can be affected too.
Estimated yearly new cases: ~228,000
5-year survival rate: ~23%
3. Prostate Cancer
The most common cancer in men. Typically slow-growing, but may lead to serious complications if undetected.
Estimated yearly new cases: ~165,000
5-year survival rate: ~98%
4. Colorectal Cancer (Colon & Rectal)
Includes cancers of the colon and rectum, which together form the large intestine.
Estimated yearly new cases: ~145,000
5-year survival rate: ~64%
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5. Melanoma (Skin Cancer)
Cancer of the pigment-producing cells in the skin. May also affect eyes and other pigmented tissues.
Estimated yearly new cases: ~96,000
5-year survival rate: ~92%
6. Bladder Cancer
Typically affects older adults, and occurs more often in men than women.
Estimated yearly new cases: ~80,000
5-year survival rate: ~77%
7. Non-Hodgkin’s Lymphoma
Cancer that begins in the lymphatic system, forming tumors from white blood cells (lymphocytes).
Estimated yearly new cases: ~74,000
5-year survival rate: ~71%
8. Kidney Cancer
Usually renal cell carcinoma. May develop as a single tumor in one kidney or in the renal pelvis.
Estimated yearly new cases: ~74,000
5-year survival rate: ~75%
9. Endometrial Cancer
Cancer of the uterine lining. Affects mostly postmenopausal women.
Estimated yearly new cases: ~62,000
5-year survival rate: ~84%
10. Leukemia (All Types)
Blood cancers originating in the bone marrow. Interfere with normal blood cell function.
Estimated yearly new cases: ~62,000
5-year survival rate: ~61%
11. Pancreatic Cancer
Often diagnosed in later stages. Spreads quickly and has one of the lowest survival rates.
Estimated yearly new cases: ~57,000
5-year survival rate: ~9%
12. Thyroid Cancer
Most types are treatable with high success. Anaplastic is the most aggressive, while papillary is most common.
Estimated yearly new cases: ~52,000
5-year survival rate: Nearly 100%
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13. Liver & Bile Duct Cancer
Includes hepatocellular carcinoma and bile duct cancers. Risk increases with liver disease and viral hepatitis.
Estimated yearly new cases: ~42,000
5-year survival rate: ~18%
📊 Understanding Survival Rates
The 5-year survival rate refers to the percentage of people who live at least five years after being diagnosed. These numbers vary greatly depending on cancer type, stage, treatment access, and individual health.
🧠 Key Takeaways
- These 13 cancers represent over 70% of all diagnosed cases annually.
- Many cancers—especially breast, prostate, and thyroid—have high survival rates if caught early.
- Cancers like pancreatic, liver, and lung remain harder to treat, emphasizing the need for early detection.
- Healthy lifestyle habits, screenings, and timely care are crucial in preventing and managing cancer risk.
💬 What You Can Do
If you’re experiencing persistent symptoms or have a family history of any of these cancers, consult a doctor for early screening. Additionally, explore supportive products that may assist during prevention, treatment, or recovery.
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