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Celkeran (Chlorambucil)

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Celkeran (Chlorambucil Tablets) contains chlorambucil, an oral alkylating chemotherapy agent used to treat chronic lymphocytic leukemia (CLL) and certain non‑Hodgkin lymphomas. By cross-linking DNA strands, Celkeran disrupts cancer cell replication. Administered under oncologist supervision, it is often used in low-dose continuous regimens to balance efficacy and tolerability.

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Key Benefits

  • Alkylates DNA to block cancer cell division

  • Approved for CLL and select lymphomas

  • Oral dosing for outpatient convenience

  • Low-dose regimens reduce side effects while maintaining efficacy

  • Clinical track record of disease control under medical guidance


🎯 How to Use

  • Adults: Typically 0.1 mg/kg daily or per cycle-based protocol

  • Swallow tablets with water—don’t crush or chew

  • Adhere strictly to regimen (daily or cyclical) as instructed

  • Monitor blood counts, liver, and kidney function regularly

  • Store in a cool, dry place away from children


⚠️ Precautions

  • Prescription chemotherapy—use only under specialist care

  • Monitor for bone marrow suppression and organ function

  • Not safe during pregnancy or breastfeeding

  • Avoid live vaccines during therapy

  • Discontinue and seek medical attention if infection, bleeding, or severe side effects occur


🤕 Possible Side Effects

  • Common: Low white cells, anemia, nausea, fatigue, mouth sores

  • Occasional: Skin rash, elevated liver enzymes, diarrhea

  • Rare but serious: Sepsis, severe cytopenias, allergic reactions—seek urgent care if symptoms appear


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Frequently Asked Questions (FAQs)

Q. What is Celkeran used for?
A. Celkeran treats chronic lymphocytic leukemia and select lymphomas by inhibiting DNA replication.

Q. How should it be taken?
A. Taken orally at prescribed low daily or cyclical doses by your oncologist.

Q. Is monitoring required during therapy?
A. Yes—monitor blood counts, liver and kidney function frequently.

Q. Can it be used during pregnancy?
A. No—chlorambucil is unsafe during pregnancy and breastfeeding.

Dose

2 MG, 5 MG

Pack Size

30 Tablet, 60 Tablet, 90 Tablet

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