Dacilon 0.5 mg (Dactinomycin)

✅ Key Benefits

• Targets rapidly dividing tumor cells via transcription inhibition

• Approved for multiple pediatric and adult cancers

• Used in combination chemotherapy protocols (e.g., VAC, BEP)

• Delivered via IV injection in cancer treatment centers

• Proven efficacy with established oncology protocols

🎯 How to Use

• Adults & pediatrics: Dose based on body surface area (e.g., 15 mcg/kg/day for 5 days) per protocol

• Administer intravenously; do not mix with alkaline solutions

• Must be given by qualified healthcare professionals in controlled settings

• Monitor blood counts, liver, and renal function regularly during treatment

• Store vials refrigerated, protected from light

⚠️ Precautions

• Prescription injectable—administer only in clinical settings

• Monitor for myelosuppression, hepatotoxicity, mucositis

• Avoid during pregnancy unless benefits justify risk; contraindicated in breastfeeding

• Use supportive measures for nausea, infection risk, and organ monitoring

• Discontinue and seek immediate care if severe myelosuppression, infection, or organ toxicity occurs

🤕 Possible Side Effects

• Common: Myelosuppression (neutropenia), nausea, vomiting, mucositis, diarrhea

• Occasional: Elevated liver enzymes, rash, fever

• Rare but serious: Sepsis, hepatic failure, severe mucositis—seek urgent care if noted

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❓ Frequently Asked Questions (FAQs)

Q. What cancers does Dacilon treat?
A. Treats Wilms’ tumor, rhabdomyosarcoma, Ewing’s sarcoma, gestational trophoblastic disease, testicular cancer, and others in chemotherapy regimens.

Q. How is it administered?
A. Given as an intravenous injection based on body surface area, under clinician supervision.

Q. Is monitoring required?
A. Yes—monitor blood counts, liver and kidney function, and signs of infection throughout treatment.

Q. Can it be used during pregnancy?
A. Generally avoided; only used if potential benefits outweigh risks and under specialized medical guidance.