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Lupride Depot (Leuprolide Acetate Depot)

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Lupride Depot (Leuprolide Acetate Depot Injection) contains leuprolide, a gonadotropin-releasing hormone (GnRH) agonist injected intramuscularly or subcutaneously in depot form. It suppresses LH/FSH and sex hormones, managing prostate cancer, endometriosis, uterine fibroids, and central precocious puberty under medical supervision. Long-acting depot formulations enable monthly to quarterly dosing.

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Key Benefits

  • Suppresses sex hormone production for various conditions

  • Appropriate for prostate cancer, endometriosis, fibroids, and puberty disorders

  • Depot form offers long-acting monthly to quarterly dosing

  • Reduces need for frequent injections and enhances compliance

  • Administered by healthcare professionals in outpatient settings


🎯 How to Use

  • Adults & pediatrics: Dose varies by condition and duration—typically 3.75 mg monthly or up to 22.5 mg quarterly

  • Administer IM or SC as per provider

  • Monitor hormone levels, bone density, and symptom response

  • Store refrigerated; allow vial to reach room temperature before use


⚠️ Precautions

  • Prescription injectable—administer under specialist care

  • Monitor for menopausal symptoms (hot flashes), bone density loss, and mood changes

  • Not recommended in pregnancy or breastfeeding

  • Use contraception when indicated until hormone suppression confirmed

  • Discontinue and consult provider if severe bone pain, vision changes, or allergic reactions occur


🤕 Possible Side Effects

  • Common: Hot flushes, mood changes, injection site pain, headache

  • Occasional: Decreased libido, bone density reduction, weight gain

  • Rare but serious: Osteoporosis progression, pituitary apoplexy, severe mood or cardiovascular changes—seek medical attention if occurs


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Frequently Asked Questions (FAQs)

Q. What is Lupride Depot used for?
A. It treats prostate cancer, endometriosis, uterine fibroids, and central precocious puberty by suppressing sex hormones.

Q. How often is Lupride Depot administered?
A. Monthly or quarterly depending on formulation and condition, per specialist instructions.

Q. Are tests required?
A. Yes—monitor sex hormone levels, bone density, symptoms, and heart health periodically.

Q. Can Lupride Depot be used during pregnancy?
A. No—it’s contraindicated in pregnancy and breastfeeding.

Dose

3.75 MG, 11.25 MG, 22.50 MG

Pack Size

1 Injection, 2 Injection, 3 Injection

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