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Oxitan (Oxaliplatin )

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Oxitan (Oxaliplatin Injection) contains oxaliplatin, a platinum-based chemotherapy agent used to treat colorectal, pancreatic, and gastric cancers. It forms DNA crosslinks, impairing cancer cell replication. Oxitan is administered intravenously, often in combination regimens like FOLFOX, under oncologist supervision for outpatient infusion therapy.

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Key Benefits

  • Forms DNA crosslinks to inhibit tumor growth

  • Approved for colorectal, pancreatic, and gastric cancers

  • Commonly used in combination protocols (e.g., FOLFOX)

  • Administered via IV infusion in outpatient settings

  • Comprehensive efficacy data in solid tumor oncology


🎯 How to Use

  • Adults: Typical dose 85 mg/m² IV infusion over 2 hours every 2 weeks (FOLFOX regimen)

  • Administer with IV hydration and antiemetics per protocol

  • Given in clinical setting by oncology-trained staff

  • Monitor blood counts, kidney function, and neurologic symptoms before each cycle

  • Store refrigerated, protect from light, and maintain sterility


⚠️ Precautions

  • Prescription injectable—administer only by healthcare professionals

  • Monitor for neurotoxicity (cold-triggered), nephrotoxicity, myelosuppression

  • Provide pre- and post-infusion hydration

  • Avoid during pregnancy and breastfeeding unless essential and supervised

  • Discontinue and seek immediate care for severe neuropathy, hypersensitivity, or organ dysfunction


🤕 Possible Side Effects

  • Common: Peripheral neuropathy (cold-induced), nausea, diarrhea, low blood counts

  • Occasional: Liver enzyme elevation, mucositis, fatigue

  • Rare but serious: Severe neurotoxicity, anaphylaxis, renal impairment—seek urgent attention if these occur


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Frequently Asked Questions (FAQs)

Q. What cancers does Oxitan treat?
A. It’s used in combination regimens for colorectal, pancreatic, and gastric cancers with platinum-based therapy.

Q. How often is it given?
A. Administered every two weeks (e.g., 85 mg/m²) within FOLFOX or oxaliplatin-based schedules, with hydration and antiemetics.

Q. Is monitoring required?
A. Yes—kidney function, blood counts, neurologic status, and hepatic monitoring before each cycle.

Q. Can it be used during pregnancy?
A. No—it’s contraindicated during pregnancy and breastfeeding unless essential under strict guidance.

Dose

25 ML, 50 ML

Pack Size

1 Injection, 2 Injection, 3 Injection

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