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Palbace 125 mg (Palbociclib)

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Palbace (Palbociclib Capsules) contains palbociclib, an oral CDK4/6 inhibitor used alongside endocrine therapy for hormone receptor–positive, HER2-negative advanced or metastatic breast cancer. Taken in 21-day cycles (21 days on, 7 days off), Palbace helps slow cancer progression and prolongs progression-free survival under oncologist supervision.

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✅ Key Benefits

Targets CDK4/6 to halt cancer cell proliferation
Effective when combined with letrozole or fulvestrant in HR+/HER2– advanced breast cancer
Oral capsule format for outpatient convenience
Proven to significantly extend progression-free survival
Manageable safety profile with routine monitoring

🎯 How to Use

Adults: 125 mg daily for 21 days, followed by a 7-day break; repeat in 28-day cycles
Take with food and water—do not crush or chew
Monitor complete blood count before each cycle and periodically
Track liver function and watch for signs of infection
Store in a cool, dry place—keep out of children’s reach

⚠️ Precautions

Prescription-only therapy—administer under specialist care
Monitor for neutropenia, infections, and liver enzyme changes
Avoid use during pregnancy and breastfeeding—use contraception
Adjust dose in the event of severe blood count or liver abnormalities
Discontinue and seek medical care if febrile neutropenia, severe infection, or liver issues occur

🤕 Possible Side Effects

Common: Neutropenia, fatigue, nausea, diarrhea, low blood counts
Occasional: Upper respiratory infection, stomatitis, elevated liver enzymes
Rare but serious: Febrile neutropenia, severe infection—seek medical care if symptoms occur

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❓ Frequently Asked Questions (FAQs)

Q. What is Palbace used for?
A. Used in HR+/HER2– advanced breast cancer in combination with endocrine therapy to inhibit CDK4/6 and slow disease progression.

Q. How is the regimen structured?
A. Taken 125 mg Palbace daily for 21 days with endocrine therapy, followed by 7-day drug holiday; cycles repeat every 28 days.

Q. Is monitoring required?
A. Yes—check blood counts and liver function before each cycle and adjust dosing as needed.

Q. Can Palbace be used if pregnant?
A. No—it’s contraindicated during pregnancy and breastfeeding; effective contraception is required.