Rapact (Everolimus)

✅ Key Benefits

• Suppresses mTOR pathway to inhibit tumor cell proliferation

• Approved indications: kidney, breast, neuroendocrine tumors, and TSC-associated tumors

• Oral once-daily dosing for outpatient treatment

• Demonstrated improvement in progression-free survival

• Administered under clinician monitoring with established safety profile

🎯 How to Use

• Adults: Common dose 10 mg once daily; breast cancer combo uses 10 mg daily with exemestane

• Swallow whole with water—do not crush or chew

• Take consistently each day

• Monitor blood counts, liver and renal function, lipid profile, and glucose

• Store in a cool, dry place—keep away from children

⚠️ Precautions

• Prescription-only targeted therapy—use under specialist supervision

• Monitor infections risk, pulmonary symptoms, metabolic changes, and mucositis

• Avoid during pregnancy or breastfeeding—use contraception

• Adjust dose for severe hepatic impairment

• Discontinue and seek medical attention if severe infections, non-healing wounds, or pulmonary issues occur

🤕 Possible Side Effects

• Common: Stomatitis, infections, rash, fatigue, edema

• Occasional: Hyperglycemia, hyperlipidemia, pneumonitis

• Rare but serious: Non-infectious pneumonitis, severe infections—seek medical care if experienced

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❓ Frequently Asked Questions (FAQs)

Q. What is Rapact used for?
A. Rapact treats certain kidney, breast, neuroendocrine tumors, and TSC-related tumors by targeting the mTOR pathway.

Q. How is it taken?
A. 10 mg once daily; in breast cancer it’s combined with exemestane—follow specialist’s guidance.

Q. Is monitoring required?
A. Yes—check blood counts, metabolic panels, pulmonary health regularly.

Q. Can it be used during pregnancy?
A. No—it’s contraindicated during pregnancy and breastfeeding; contraception recommended.