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Sorafenat 200 mg (Sorafenib)

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Sorafenat (Sorafenib Tablets) contains sorafenib, an oral multi-kinase inhibitor targeting RAF, VEGFR, PDGFR, and KIT pathways. It’s used to treat unresectable hepatocellular carcinoma, advanced renal cell carcinoma, and differentiated thyroid carcinoma under specialist supervision. Sorafenat helps slow tumor growth and reduce angiogenesis.

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✅ Key Benefits

Blocks RAF, VEGFR, PDGFR, KIT to curb tumor proliferation & angiogenesis
Approved for liver, kidney, and thyroid cancers
Convenient oral tablet supports outpatient use
Demonstrated to improve survival and disease control
Regular dosing under oncologist guidance ensures safety & efficacy

🎯 How to Use

Adults: 200 mg twice daily, taken approximately 12 hours apart; may adjust for tolerance
Swallow tablets whole with water—do not crush or chew
Take with low-fat meal or plain water; maintain consistent dosing schedule
Monitor liver function, blood pressure, skin exam, and ECG regularly
Store in a cool, dry place—keep out of children’s reach

⚠️ Precautions

Prescription-only targeted therapy—use under specialist oncology care
Monitor for hepatotoxicity, hypertension, skin rash, and bleeding
Avoid during pregnancy or breastfeeding—use effective contraception
Adjust dose or interrupt treatment if severe toxicity occurs
Discontinue and seek immediate medical attention for severe liver injury, cardiotoxicity, or GI perforation

🤕 Possible Side Effects

Common: Hand–foot skin reaction, hypertension, diarrhea, fatigue, rash
Occasional: Weight loss, alopecia, elevated liver enzymes
Rare but serious: Severe liver failure, bleeding, cardiac ischemia, GI perforation—seek prompt care if symptoms arise

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❓ Frequently Asked Questions (FAQs)

Q. What is Sorafenat used for?
A. It treats unresectable liver cancer, advanced kidney cancer, and certain thyroid cancers using multi-kinase inhibition.

Q. How is it taken?
A. Typically 200 mg orally twice daily, spaced about 12 hours apart—dosing may adjust based on tolerance.

Q. Is monitoring required during use?
A. Yes—regular checks of liver function, blood pressure, skin, ECG, and potential side effects are essential.

Q. Can Sorafenat be used during pregnancy?
A. No—avoid during pregnancy or breastfeeding; contraception is required.