Spexib (Ceritinib)

✅ Key Benefits

• Potent inhibition of ALK-driven tumor growth

• Effective in ALK-positive NSCLC, including crizotinib-resistant cases

• Oral once-daily dosing for patient convenience

• Extends progression-free survival with documented efficacy

• Well-tolerated with manageable side effect profile under care team oversight

🎯 How to Use

• Adults: 450 mg once daily with a low-fat meal (as prescribed)

• Swallow tablets whole—do not crush or chew

• Maintain daily schedule for consistent drug exposure

• Monitor liver function, ECG, and gastrointestinal symptoms

• Store in a cool, dry place away from children

⚠️ Precautions

• Prescription-only oncology medication—use under specialist supervision

• Monitor for hepatotoxicity, QT prolongation, GI effects

• Not recommended during pregnancy or breastfeeding

• Check for drug interactions, especially CYP3A inhibitors or inducers

• Discontinue and consult provider if severe diarrhea, cardiac symptoms, or liver issues occur

🤕 Possible Side Effects

• Common: Diarrhea, nausea, vomiting, elevated liver enzymes, fatigue

• Occasional: Abdominal pain, rash, edema, headache

• Rare but serious: Interstitial lung disease, QT prolongation, liver failure—seek urgent care if severe symptoms arise

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❓ Frequently Asked Questions (FAQs)

Q. What is Spexib used for?
A. Spexib treats ALK-positive non-small cell lung cancer, including cases that resist crizotinib.

Q. How is it taken?
A. One 450 mg tablet once daily with food, as directed by your oncologist.

Q. Is monitoring needed?
A. Yes—liver enzymes, ECG, ECG, and GI status should be checked regularly.

Q. Can it be taken during pregnancy?
A. No—avoid during pregnancy or breastfeeding due to fetal risk.